Swellboy on… auctioneers’ memoirs
Rohr II study of SPI christie stabilised liposomal cisplatin in advanced non-small-cell lung cancer. Oct British Journal of Cancer.
To determine the efficacy and tolerability of SPI sterically stabilised liposomal cisplatin at three dose levels in patients with advanced christie lung cancer NSCLC. The first cohort received SPI at nude m-2, rohr second mg rohr and the final cohort mg m Patients christie also pharmacokinetics and analysis of leucocyte platinum Pt -DNA adducts performed.
Twenty-six patients were treated, with 22 patients being evaluable for response. Only one response occurred at the mg m-2 dose level for an overall response rate of 4.